mouse neuroblastoma cell line n2a (ATCC)
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Mouse Neuroblastoma Cell Line N2a, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 4244 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+neuroblastoma+cell+line+n2a/Neuro-2a/pm42120407-428-0-5
Average 99 stars, based on 4244 article reviews
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Cell Culture:Article Title: H3K4 Trimethylation Mediate Hyperhomocysteinemia Induced Neurodegeneration via Suppressing Histone Acetylation by ANP32A. Article Snippet: Homocysteine (Hcy) is an independent and serious risk factor for dementia, including Alzheimer’s disease (AD), but the precise mechanisms are still poorly understood.. In the current study, we observed that the permissive histone mark trimethyl histone H3 lysine 4 (H3K4me3) and its methyltransferase KMT2B were significantly elevated in hyperhomocysteinemia (HHcy) rats, with impairment of synaptic plasticity and cognitive function.. Further research found that histone methylation inhibited synapse-associated protein expression, by suppressing histone acetylation. Article Title: Preformed fibrils of α-synuclein rapidly activate LRRK2 on early endosomes, driving Rab5 phosphorylation and disrupting endolysosomal and synaptic function. Article Snippet: .. other:Article Title: Distinct pathophysiological mechanisms of CEP152 variants in microcephaly and brain abnormalities. Article Snippet: Alexa Fluor 488-, 568-, and 647-labeled IgG (Abcam, Cat# ab150077, ab175471, and ab150075, respectively) were used as secondary antibodies at a 1:1000 dilution. |
