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mouse neuroblastoma cell line n2a  (ATCC)


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    ATCC mouse neuroblastoma cell line n2a
    Mouse Neuroblastoma Cell Line N2a, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 4244 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mouse+neuroblastoma+cell+line+n2a/Neuro-2a/pm42120407-428-0-5
    Average 99 stars, based on 4244 article reviews
    mouse neuroblastoma cell line n2a - by Bioz Stars, 2026-10
    99/100 stars

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    Cell Culture:

    Article Title: H3K4 Trimethylation Mediate Hyperhomocysteinemia Induced Neurodegeneration via Suppressing Histone Acetylation by ANP32A.
    Article Snippet: Homocysteine (Hcy) is an independent and serious risk factor for dementia, including Alzheimer’s disease (AD), but the precise mechanisms are still poorly understood.. In the current study, we observed that the permissive histone mark trimethyl histone H3 lysine 4 (H3K4me3) and its methyltransferase KMT2B were significantly elevated in hyperhomocysteinemia (HHcy) rats, with impairment of synaptic plasticity and cognitive function.. Further research found that histone methylation inhibited synapse-associated protein expression, by suppressing histone acetylation.

    Article Title: Preformed fibrils of α-synuclein rapidly activate LRRK2 on early endosomes, driving Rab5 phosphorylation and disrupting endolysosomal and synaptic function.
    Article Snippet: .. Mouse neuroblastoma cell line N2a (ATCC; Cat# CCL-131) and human embryonic kidney cell line HEK293T (ATCC; Cat# CRL-3216) were cultured in DMEM medium (Gibco) supplemented with 10% FBS (Omega Scientific; Cat# FB-02) and 1% Penicillin-Streptomycin (Gibco). ..

    other:

    Article Title: Distinct pathophysiological mechanisms of CEP152 variants in microcephaly and brain abnormalities.
    Article Snippet: Alexa Fluor 488-, 568-, and 647-labeled IgG (Abcam, Cat# ab150077, ab175471, and ab150075, respectively) were used as secondary antibodies at a 1:1000 dilution.



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    ATCC mouse neuroblastoma cell line n2a
    Mouse Neuroblastoma Cell Line N2a, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    ATCC neuro 2a n2a mouse neuroblastoma cell lines
    Abcam ab64186 recognizes NRN1 protein in mouse <t>neuroblastoma</t> cells. (A) Representative Western blot of human embryonic kidney (HEK) <t>293T,</t> <t>Neuro‐2a</t> <t>(N2a)</t> mouse neuroblastoma, and SH‐SY5Y human neuroblastoma cell lysates (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186 and GAPDH monoclonal antibody. (B) N2a cells were transfected with NRN1 or Scramble (non‐targeting) siRNA smart pools and harvested after 96 h. Western blot analyses with NRN1 polyclonal antibody Abcam ab64186 revealed reduced intensity of the ∼34 kDa band in NRN1‐depleted cells, compared to Scramble control. 10 µg of protein was loaded per lane, and GAPDH was probed as a loading control. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; NRN1, Neuritin‐1; siRNA, small interfering RNA;
    Neuro 2a N2a Mouse Neuroblastoma Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    ATCC n2a mouse neuroblastoma cell line
    Abcam ab64186 recognizes NRN1 protein in mouse <t>neuroblastoma</t> cells. (A) Representative Western blot of human embryonic kidney (HEK) <t>293T,</t> <t>Neuro‐2a</t> <t>(N2a)</t> mouse neuroblastoma, and SH‐SY5Y human neuroblastoma cell lysates (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186 and GAPDH monoclonal antibody. (B) N2a cells were transfected with NRN1 or Scramble (non‐targeting) siRNA smart pools and harvested after 96 h. Western blot analyses with NRN1 polyclonal antibody Abcam ab64186 revealed reduced intensity of the ∼34 kDa band in NRN1‐depleted cells, compared to Scramble control. 10 µg of protein was loaded per lane, and GAPDH was probed as a loading control. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; NRN1, Neuritin‐1; siRNA, small interfering RNA;
    N2a Mouse Neuroblastoma Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    ATCC mouse n2a neuroblastoma ccl 131 cell lines
    Abcam ab64186 recognizes NRN1 protein in mouse <t>neuroblastoma</t> cells. (A) Representative Western blot of human embryonic kidney (HEK) <t>293T,</t> <t>Neuro‐2a</t> <t>(N2a)</t> mouse neuroblastoma, and SH‐SY5Y human neuroblastoma cell lysates (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186 and GAPDH monoclonal antibody. (B) N2a cells were transfected with NRN1 or Scramble (non‐targeting) siRNA smart pools and harvested after 96 h. Western blot analyses with NRN1 polyclonal antibody Abcam ab64186 revealed reduced intensity of the ∼34 kDa band in NRN1‐depleted cells, compared to Scramble control. 10 µg of protein was loaded per lane, and GAPDH was probed as a loading control. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; NRN1, Neuritin‐1; siRNA, small interfering RNA;
    Mouse N2a Neuroblastoma Ccl 131 Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 99 stars, based on 1 article reviews
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    Abcam ab64186 recognizes NRN1 protein in mouse neuroblastoma cells. (A) Representative Western blot of human embryonic kidney (HEK) 293T, Neuro‐2a (N2a) mouse neuroblastoma, and SH‐SY5Y human neuroblastoma cell lysates (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186 and GAPDH monoclonal antibody. (B) N2a cells were transfected with NRN1 or Scramble (non‐targeting) siRNA smart pools and harvested after 96 h. Western blot analyses with NRN1 polyclonal antibody Abcam ab64186 revealed reduced intensity of the ∼34 kDa band in NRN1‐depleted cells, compared to Scramble control. 10 µg of protein was loaded per lane, and GAPDH was probed as a loading control. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; NRN1, Neuritin‐1; siRNA, small interfering RNA;

    Journal: Alzheimer's & Dementia

    Article Title: NRN1 as a therapeutic target for Alzheimer's disease

    doi: 10.1002/alz.71149

    Figure Lengend Snippet: Abcam ab64186 recognizes NRN1 protein in mouse neuroblastoma cells. (A) Representative Western blot of human embryonic kidney (HEK) 293T, Neuro‐2a (N2a) mouse neuroblastoma, and SH‐SY5Y human neuroblastoma cell lysates (50 µg protein), probed with NRN1 polyclonal antibody Abcam ab64186 and GAPDH monoclonal antibody. (B) N2a cells were transfected with NRN1 or Scramble (non‐targeting) siRNA smart pools and harvested after 96 h. Western blot analyses with NRN1 polyclonal antibody Abcam ab64186 revealed reduced intensity of the ∼34 kDa band in NRN1‐depleted cells, compared to Scramble control. 10 µg of protein was loaded per lane, and GAPDH was probed as a loading control. GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; NRN1, Neuritin‐1; siRNA, small interfering RNA;

    Article Snippet: Neuro‐2a (N2a) mouse neuroblastoma cell lines (Catalog No.: CCL‐131, ATCC) were maintained in MEM (Catalog No.: 11095‐080, Thermo Fisher Scientific) with 10% FBS and 1% penicillin‐streptomycin.

    Techniques: Western Blot, Transfection, Control, Small Interfering RNA